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KeWei Wang
2016-05-09   审核人:

Dr. KeWei Wang is an endowed ChangJiang Professor and the Dean of School of Pharmacy at Qingdao University. Dr. Wang graduated with M.D. in medicine and obtained his Ph.D. in neurophysiology from Peking University Medical School in 1988. From 1988 to 1997, he went to University of Cambridge and then Yale University for postdoctoral training in the disciplines of pharmacology, biophysics and physiology. From 1997 to 2005, he as a Principal Scientist/team leader worked at Wyeth Neuroscience, Princeton, on target identification/validation and screening of novel ion channel modulators for CNS drug discovery/research. From 2005-2014, he was a Professor in the Department of Neurobiology at Medical School and also served as a Chair of the Department of Molecular and Cellular Pharmacology at Peking University School of Pharmaceutical Sciences.

The overall research in his lab is directed towards understanding structure and modulation of ion channels, and identification and validation of ion channel targets and their modulators that have therapeutic potential for treatment of neuropsychiatric disorders such as pain, epilepsy, schizophrenia, stroke and depression. Currently, two classes of ion channels, voltage-gated potassium (Kv) and ligand-gated TRP channels, are being investigated in the lab for their roles in modulation of neurological function and pathophysiology in the brain using electrophysiology, confocal Ca2+/FRET imaging with combination of molecular biology, structural biology and in vivo pharmacology.  

He published over 80 peer-reviewed articles in journals such as NEURON, NATURE NEUROSCI, PNAS, NATURE, JBC, and BIOPHYSIOL J. etc, and was granted for 7 patents. He currently serves a Board Member and editor for Handbook of Experimental Pharmacology, and a review editor for several journals including “Frontiers in Neuroscience” and Pharmaceutica Sinica B, and Acta Neurpharmacologica.

 

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